The Safe Administration of Oxytocin guideline report, developed by PCMCH in 2019, outlines best practice recommendations for the safe management of pregnant patients whose labour is induced or augmented with the medication oxytocin. The objective of the report is to reduce the risk of misuse and/or mismanagement of oxytocin by addressing risk factors that have contributed to common errors in its administration. To promote a culture of safety when using this high-alert medication, 11 best practice recommendations were identified and vetted by clinical experts.